Publication: CATALYST-FREE SYNTHESIS OF A SERIES OF DIARYLSUFONYLUREAS
| dc.contributor.author | SIVAKAMI JAYA SEELAN | |
| dc.date.accessioned | 2023-10-06T15:31:55Z | |
| dc.date.available | 2023-10-06T15:31:55Z | |
| dc.date.issued | 2023 | |
| dc.description.abstract | In comparison to traditional organic synthesis, catalyst-free synthetic techniques provide several advantages and have been proved to be environmentally friendly. Here, a facile catalyst-free procedure for the synthesis of derivatives of diarylsulfonylureas was developed. The simple process involves reacting p-toluenesulfonyl isocyanate with various substituted primary amines in the presence of dichloromethane as the solvent at room temperature to produce the desired diarylsulfonylureas derivatives. Nine compounds with up to 94% yield have been synthesized successfully through this protocol. These products' structures were characterised using a variety of techniques, including fourier-transform infrared spectroscopy, mass spectroscopy, nuclear magnetic resonance spectroscopy, physical analysis, and melting point. Overall, this method has many benefits, including convenient room temperature synthesis, a straightforward workup procedure, rapid reaction times, and quantifiable reaction yields. Keywords: Diarylsulfonylureas, Green Chemistry, Catalyst-Free, Room Temperature synthesis | en_US |
| dc.identifier.uri | https://hdl.handle.net/20.500.14377/32188 | |
| dc.language.iso | en | en_US |
| dc.publisher | International Medical University | en_US |
| dc.subject | Chemistry Techniques, Synthetic | en_US |
| dc.subject | Magnetic Resonance Spectroscopy | en_US |
| dc.subject | Spectroscopy, Fourier Transform Infrared | en_US |
| dc.subject | Environmental Pollutants | en_US |
| dc.subject | Photosynthesis | en_US |
| dc.title | CATALYST-FREE SYNTHESIS OF A SERIES OF DIARYLSUFONYLUREAS | en_US |
| dc.type | Thesis | |
| dspace.entity.type | Publication |